How to Disappear Mouse

[A Frail Ol Lady]

I am trying to play Land of The Dead for my MacBook Pro, and the game works, fine. There is only one thing, I cannot have the Mac's mouse disappear, and it doesn't let me turn around all the way, or allow me to click any of the menu items. Please help, I really have no idea of Wine, or how it works, so try to be simple for the nub (me)! Thanks