I have already opened a ticket here but with no success. But I want to know the opinion of more people to know if I'm wrong.
On Ubuntu (64 bit on my system) the packages wine1.4 (from the official Ubuntu repository) and wine1.5 (from the official WineHQ ppa) doesn't depend on libxcursor1:i386. Normally this is not a problem because this package is a recommendation and an Ubuntu installation does install all recommendations at default. This will be only a problem if the option --no-install-recommends with apt or the configuration APT::Install-Recommends 0; is used. In both cases apt doesn't install any recommended packages anymore which is good if you want to have a minimalistic system without optional applications installed.
The problem is that libxcursor1:i386 isn't installed anymore too. This will result in some currupted cursor graphics (for example Diablo 3 and Guild Wars). In my opinion this is a part of core functionality and should be a dependecy because of this.
Dependencies of Wine
Re: Dependencies of Wine
Binary packages are created by the distros, and you already have an answer from your distro package maintainer.