I had my setup working and after 9.22 staging install plugin knobs are no longer working.
I solved months ago this thing, it was about not having dxvk configured.
Since then, I think I had only occasional hiccups, shortly solved because it was something stupid.
This time, I can't figure out what's going on

Debian 12, Wine 9.22, REAPER 7 native, Yabridge 5.1.1.
Everything was working before updating to 9.22. Now trying to revert to 9.21 and see that happens, but I'm afraid in the meanwhile I tweaked a lot and my prefix could be screwed.
Sorry for the rant, this Wine thing sometimes truly seems a puzzle pyramid made of glass pieces...
- Mario