Will nvidia affect the operation of wine?

[XXTXTOP]

I found that when I use nvidia 1650s alone, it will be very lag when running wine, but it will be much smoother when running amd graphics card and nvidia at the same time.
what should I do?

This is my program running environment：

Code: Select all

 5.10.0-9-amd64 #1 SMP Debian 5.10.70-1 (2021-09-30) x86_64 GNU/Linux   wine-6.20

Sorry i'm not very good at english，Thanks everyone.