Software works great for the most part, after installing all the needed libraries with Winetricks.
Problem is, I cannot activate these checkboxes correctly. They do not respond to my clicks, and after many clicks they may become checked but the program rarely recognizes them as active, as it should display graphics on the right but not always does:

I tried all the windows/mouse/virtual desktop options in the graphics tab of winecfg but none of those setting seems to affect this problem.
Any ideas?
Thank you so much in advance